Publications

29 August 2024

The contribution of porins to enterobacterial drug resistance

Anne Davin-Regli, Jean-Marie Pagès, Julia Vergalli

15 July 2024

Optimization of Solid Lipid Nanoparticle Formulation for Cosmetic Application Using Design of Experiments, PART II: Physical Characterization and In Vitro Skin Permeation for Sesamol Skin Delivery

Margot Cassayre, Auriane Oline ,Caroline Orneto, Emmanuel Wafo, Lydia Abou, Alexandre Altié, Magalie Claeys-Bruno, Christophe Sauzet, Philippe Piccerelle

17 Jun 2024

C9-Functionalized Doxycycline Analogs as Drug Candidates to Prevent Pathological α-Synuclein Aggregation and Neuroinflammation in Parkinson's Disease Degeneration. ChemMedChem.

Rose C, Tomas-Grau RH, Zabala B, Michel PP, Brunel JM, Chehín R, Raisman-Vozari R, Ferrié L, Figadère B.

24 March 2024

Computational Methods Reveal a Series of Cyclic and Linear Lichenysins and Surfactins from the Vietnamese Marine Sediment-Derived Streptomyces Strain G222

Andrea Castaldi, Bich Ngan Truong, Quyen Thi Vu, Thi Hong Minh Le, Arul Marie, Gaël Le Pennec, Florent Rouvier, Jean-Michel Brunel, Arlette Longeon, Van Cuong Pham, Thi Mai Huong Doan, Marie-Lise Bourguet-Kondracki

22 Feb 2024

Antimicrobial Indole-3-Carboxamido-Polyamine Conjugates Target Bacterial Membranes and Are Antibiotic Potentiators. Biomolecules

Sue K, Cadelis MM, Rouvier F, Bourguet-Kondracki ML, Brunel JM, Copp BR

15 May 2023

Acacia Senegal Budmunchiamines as a Potential Adjuvant for Rejuvenating Phenicol Activities towards Escherichia Coli-Resistant Strains

René Dofini Magnini, François Pedinielli, Julia Vergalli, Noufou Ouedraogo, Simon Remy, Adama Hilou, Jean-Michel Brunel, Jean-Marie Pagès, Anne Davin-Regli

27 April 2023

Contribution of efflux and mutations in fluoroquinolone susceptibility in MDR enterobacterial isolates: a quantitative and molecular study

Aurélie Ferrand, Julia Vergalli, Claude Bosi, Alix Pantel, Jean-Marie Pagès, Anne Davin-Regli

05 October 2022

Cephalosporin translocation across enterobacterial OmpF and OmpC channels, a filter across the outer membrane

Muriel Masi, Julia Vergalli, Ishan Ghai, Andrea Barba-Bon, Thérèse Schembri, Werner M. Nau, Daniel Lafitte, Mathias Winterhalter & Jean-Marie Pagès

12 January 2023

Rejuvenating the Activity of Usual Antibiotics on Resistant Gram-Negative Bacteria: Recent Issues and Perspectives

Jinane Tabcheh, Julia Vergalli, Anne Davin-Régli, Noha Ghanem, Jean-Marie Pages, Charbel Al-Bayssari, Jean Michel Brunel

20 December 2023

Antibiofilm and Antivirulence Properties of 6-Polyaminosteroid Derivatives against Antibiotic-Resistant Bacteria

Delphine Vergoz, Hung Le, Benoit Bernay, Annick Schaumann, Magalie Barreau, Flore Nilly, Florie Desriac, Ali Tahrioui, Jean-Christophe Giard, Olivier Lesouhaitier, Sylvie Chevalier, Jean Michel Brunel, Cécile Muller, Emmanuelle Dé

17 November 2023

Preliminary SAR of Novel Pleuromutilin–Polyamine Conjugates

Sue K, Cadelis MM, Hainsworth K, Rouvier F, Bourguet-Kondracki ML, Brunel JM, Copp BR

7 August 2023

Indole-3-Acetamido-Polyamines as Antimicrobial Agents and Antibiotic Adjuvants

Sue K, Cadelis MM, Gill ES, Rouvier F, Bourguet-Kondracki ML, Brunel JM, Copp BR

7 July 2023

Exploration of Bis-Cinnamido-Polyamines as Intrinsic Antimicrobial Agents and Antibiotic Enhancers

Cadelis MM, Kim J, Rouvier F, Gill ES, Fraser K, Bourguet-Kondracki ML, Brunel JM, Copp BR

5 June 2023

Investigation of Naphthyl–Polyamine Conjugates as Antimicrobials and Antibiotic Enhancers

El-Kirat-Chatel S, Varbanov M, Retourney C, Salles E, Risler A, Brunel JM, Beaussart A

June 2023

AFM reveals the interaction and nanoscale effects imposed by squalamine on Staphylococcus epidermidis

El-Kirat-Chatel S, Varbanov M, Retourney C, Salles E, Risler A, Brunel JM, Beaussart A

31 May 2023

Structure–Activity Relationship Studies of Indolglyoxyl-Polyamine Conjugates as Antimicrobials and Antibiotic Potentiators

Cadelis MM, Liu T, Sue K, Rouvier F, Bourguet-Kondracki ML, Brunel JM, Copp BR

23 May 2023

Scope and Limitations of Exploiting the Ability of the Chemosensitizer NV716 to Enhance the Activity of Tetracycline Derivatives against Pseudomonas aeruginosa

Draveny M, Rose C, Pinet A, Ferrié L, Figadère B, Brunel JM, Masi M

15 May 2023

Acacia senegal Budmunchiamines as a Potential Adjuvant for Rejuvenating Phenicol Activities towards Escherichia coli-Resistant Strains

Dofini Magnini R, Pedinielli F, Vergalli J, Ouedraogo N, Remy S, Hilou A, Brunel JM, Pagès JM, Davin-Regli A

10 May 2023

6-Polyaminosteroid Squalamine Analogues Display Antibacterial Activity against Resistant Pathogens

Vergoz D, Nilly F, Desriac F, Barreau M, Géry A, Lepetit C, Sichel F, Jeannot K, Giard JC, Garon D, Chevalier S, Muller C, Dé E, Brunel JM

20 March 2023

α,ω-Diacyl-Substituted Analogues of Natural and Unnatural Polyamines: Identification of Potent Bactericides That Selectively Target Bacterial Membranes

Chen D, Cadelis MM, Rouvier F, Troia T, Edmeades LR, Fraser K, Gill ES, Bourguet-Kondracki ML, Brunel JM, Copp BR

24 February 2023

Rescue of Dopamine Neurons from Iron-Dependent Ferroptosis by Doxycycline and Demeclocycline and Their Non-Antibiotic Derivatives

Tourville A, Viguier S, González-Lizárraga F, Tomas-Grau RH, Ramirez P, Brunel JM,
Dos Santos Pereira M, Del-Bel E, Chehin R, Ferrié L, Raisman-Vozari R, Figadère B, Michel PP

17 February 2023

Investigation of α,ω-Disubstituted Polyamine-Cholic Acid Conjugates Identifies Hyodeoxycholic and Chenodeoxycholic Scaffolds as Non-Toxic, Potent Antimicrobials

Sue K, Cadelis MM, Troia T, Rouvier F, Bourguet-Kondracki ML, Brunel JM, Copp BR

12 January 2023

Rejuvenating the Activity of Usual Antibiotics on Resistant Gram-Negative Bacteria: Recent Issues and Perspectives

Tabcheh J, Vergalli J, Davin-Régli A, Ghanem N, Pages JM, Al-Bayssari C, Brunel JM

6 October 2022

A Framework for Dissecting Affinities of Multidrug Efflux Transporter AcrB to Fluoroquinolones

Julia Vergalli, Hugo Chauvet, Francesco Oliva, Jelena Pajović, Giuliano Malloci, Attilio Vittorio Vargiu, Matthieu Réfrégiers, Paolo Ruggerone & Jean-Marie Pagès

29 August 2024

The contribution of porins to enterobacterial drug resistance

Davin-Regli A, Pagès JM, Vergalli

27 April 2023

Contribution of efflux and mutations in fluoroquinolone susceptibility in MDR enterobacterial isolates: a quantitative and molecular study

Ferrand A, Vergalli J, Bosi C, Pantel A, Pagès JM, Davin-Regli A

28 May 2024

RND Efflux Pump Induction: A Crucial Network Unveiling Adaptive Antibiotic Resistance Mechanisms of Gram-Negative Bacteria.

Novelli M, Bolla JM

26 March 2024

Design and Synthesis of Novel Amino and Acetamidoaurones with Antimicrobial Activities

Di Maio A, Olleik H, Courvoisier-Dezord E, Guillier S, Neulat-Ripoll F, Haudecoeur R, Bolla JM, Casanova M, Cavalier JF, Canaan S, Pique V, Charmasson Y, Baydoun E, Hijazi A, Perrier J, Maresca M, Robin M